H Miles Prince Selected Research

denileukin diftitox (Ontak)

8/2013	Duration of response in cutaneous T-cell lymphoma patients treated with denileukin diftitox: results from 3 phase III studies.
3/2013	Efficacy and safety of denileukin diftitox retreatment in patients with relapsed cutaneous T-cell lymphoma.
1/2013	Denileukin diftitox for the treatment of CD25 low-expression mycosis fungoides and Sézary syndrome.
4/2010	Phase III placebo-controlled trial of denileukin diftitox for patients with cutaneous T-cell lymphoma.
5/2004	Confirmation of the activity of the interleukin-2 fusion toxin denileukin diftitox against chemorefractory chronic lymphocytic leukemia, including cases with chromosome 17p deletions and without detectable CD25 expression.

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H Miles Prince Research Topics

Disease

48	Neoplasms (Cancer) 10/2021 - 05/2004
34	Multiple Myeloma 06/2022 - 07/2003
21	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 01/2022 - 10/2007
15	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 10/2021 - 04/2011
15	Lymphoma (Lymphomas) 11/2019 - 02/2004
13	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 10/2020 - 11/2009
11	Mycosis Fungoides 12/2021 - 04/2010
10	T-Cell Lymphoma (Lymphoma, T Cell) 05/2021 - 11/2009
10	Infections 01/2021 - 11/2004
7	Disease Progression 01/2019 - 07/2003
5	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 10/2020 - 06/2006
5	Hodgkin Disease (Hodgkin's Disease) 01/2019 - 01/2006
4	Sepsis (Septicemia) 01/2022 - 10/2011
4	Peripheral Nervous System Diseases (PNS Diseases) 12/2021 - 09/2006
4	B-Cell Lymphoma (Lymphoma, B Cell) 01/2021 - 02/2004
4	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 10/2020 - 05/2004
4	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2019 - 06/2006
4	Leukemia 05/2017 - 10/2007
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2013 - 04/2005
4	Hematologic Neoplasms (Hematological Malignancy) 10/2012 - 12/2005
3	Thrombocytopenia (Thrombopenia) 01/2022 - 11/2007
3	Pneumonia (Pneumonitis) 01/2022 - 10/2011
3	Neutropenia 01/2022 - 11/2007
3	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2019 - 08/2006
3	Lymphomatoid Papulosis 06/2015 - 05/2009
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 09/2013 - 08/2011
3	Febrile Neutropenia 02/2013 - 08/2004
2	Urinary Tract Infections (Urinary Tract Infection) 01/2022 - 12/2019
2	Primary Cutaneous Anaplastic Large Cell Lymphoma 12/2021 - 01/2017
2	Immunoglobulin Light-chain Amyloidosis 10/2021 - 06/2012
2	Sezary Syndrome (Sezary Erythroderma) 11/2019 - 01/2017
2	Cytopenia 11/2019 - 09/2008
2	Crohn Disease (Crohn's Disease) 05/2017 - 02/2011
2	Lymphadenopathy 01/2016 - 11/2015
2	Castleman Disease (Castleman's Disease) 01/2016 - 03/2010
2	Stomatitis 08/2014 - 07/2005
2	Mucositis 08/2014 - 07/2005
2	Fatigue 08/2013 - 04/2010
2	Central Nervous System Diseases (CNS Diseases) 12/2012 - 10/2009
2	Waldenstrom Macroglobulinemia (Macroglobulinemia) 12/2010 - 09/2005
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 07/2010 - 03/2007
2	Melanoma (Melanoma, Malignant) 05/2009 - 10/2007
1	Infarction (Infarctions) 01/2022
1	Pruritus (Itching) 12/2021

Drug/Important Bio-Agent (IBA)

19	Histone Deacetylase InhibitorsIBA 10/2020 - 05/2007
16	romidepsin (FK228)FDA Link 12/2017 - 11/2009
14	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 06/2005
13	Thalidomide (Thalomid)FDA Link 01/2019 - 07/2003
12	Rituximab (Mabthera)FDA Link 05/2017 - 02/2004
9	Lenalidomide (CC 5013)FDA Link 06/2022 - 10/2005
9	Bortezomib (Velcade)FDA Link 01/2019 - 08/2006
9	fludarabineIBA 05/2016 - 05/2004
8	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 05/2004
8	PanobinostatIBA 05/2014 - 07/2008
6	Methotrexate (Mexate)FDA LinkGeneric 12/2021 - 10/2006
5	Biological ProductsIBA 01/2018 - 07/2005
5	CytokinesIBA 01/2016 - 12/2005
5	Melphalan (Alkeran)FDA LinkGeneric 08/2014 - 07/2005
5	denileukin diftitox (Ontak)FDA Link 08/2013 - 05/2004
4	Brentuximab VedotinIBA 12/2021 - 01/2017
4	Prednisolone (Predate)FDA LinkGeneric 01/2021 - 04/2009
4	AntigensIBA 05/2017 - 12/2005
4	Antineoplastic Agents (Antineoplastics)IBA 11/2009 - 10/2007
3	pomalidomideIBA 01/2022 - 12/2019
3	isatuximabIBA 01/2022 - 12/2019
3	InterferonsIBA 10/2021 - 07/2003
3	Vincristine (Oncovin)FDA LinkGeneric 01/2021 - 06/2005
3	Biomarkers (Surrogate Marker)IBA 08/2020 - 01/2006
3	Pharmaceutical PreparationsIBA 02/2019 - 05/2007
3	Monoclonal AntibodiesIBA 08/2018 - 02/2004
3	Interleukin-2 (IL2)IBA 05/2017 - 05/2004
3	Chimeric Antigen ReceptorsIBA 05/2017 - 11/2013
3	Alemtuzumab (Campath)FDA Link 01/2017 - 02/2003
3	AnthracyclinesIBA 08/2014 - 07/2006
3	Histones (Histone)IBA 09/2013 - 06/2009
3	Proteins (Proteins, Gene)FDA Link 08/2013 - 07/2005
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 06/2008 - 07/2006
2	Proteasome InhibitorsIBA 01/2022 - 12/2019
2	Bexarotene (LGD1069)FDA Link 12/2021 - 01/2013
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 09/2008
2	daratumumabIBA 01/2021 - 12/2018
2	EpitopesIBA 05/2017 - 10/2010
2	Capsules (Microcapsules)IBA 06/2016 - 01/2014
2	Anti-Bacterial Agents (Antibiotics)IBA 08/2014 - 11/2012
2	Azacitidine (5 Azacytidine)FDA Link 09/2013 - 08/2011
2	DepsipeptidesIBA 06/2011 - 11/2009
2	PerforinIBA 04/2011 - 01/2008
2	Mitoxantrone (Novantrone)FDA LinkGeneric 11/2006 - 11/2004
1	elotuzumabIBA 06/2022

Therapy/Procedure

52	Therapeutics 01/2022 - 11/2004
21	Drug Therapy (Chemotherapy) 01/2019 - 08/2002
15	Stem Cell Transplantation 01/2021 - 05/2005
14	Breast Implants (Breast Implant) 10/2021 - 04/2011
5	Radiotherapy 04/2020 - 07/2009
5	Salvage Therapy 01/2015 - 09/2005
4	Immunotherapy 05/2017 - 12/2006
3	Photopheresis 01/2022 - 10/2008
2	Ligation 05/2015 - 12/2005
2	Aftercare (After-Treatment) 01/2015 - 08/2006
2	Combination Drug Therapy (Combination Chemotherapy) 08/2006 - 11/2004